Cou 20: Tr.bày coch phon loai coc thuoc t/dung tron he thong TKTV?

-Nhung thuoc t/dung giong nhu t/dungj kthich giao cam dc goi la cuong giao cam

-Nhung thuoc t/dung giong nhu t/dung cua fo giao cam dc goi la cuong fo giao cam

-nhung thuoc kom hom t/dung cua giao cam hay fu giao cam dc goi la huy giao cam hay fo giao cam

Hoat dong cua he TK la nho nhung chat trung gian hoa hoc,nen goi ten theo giai fau benh & sinh ly ko nui lon day du & chinh xac t/dung cua thuoc.Duoc ly chia he TKTV thành 2 he:

-He PU voi acetylcholin,goi la he cholinergic( gom hach giao cam,fo giao cam,hau hach fo giao cam,ban van dong co van,1 so vung tren TK trug uong)

-He PU voi adrenalin,goi là he adrenergic ( chi gom hau hach giao cam)

Cac thuoc t/dung tren he TKTV cung mang tinh dac hieu,t/dung chon loc tren receptor rieng doi voi chung -> phan loai dua theo cac receptor (diem tiep nhan dac hieu ) cua cac loai thuoc

-Cac receptor cua he cholinergic dc chia lam 2 loai:

+ Loai nhan coc doy hau hach (VD: thuoc tim,cac co tron & tuyen ngoai tiet) cun bi kthoch boi muscarinic & bi ngung hom boi atropin goi là he cam thu voi muscarinic (hay he M)

+Loai nhan doy tien hach bi kthoch boi nicotinic -> goi là he cam thu voi nicotinic ( hay he N).He nay gom hach giao cam,hach fo giao cam,tuy thuong than,xoang DM canh & ban van dong co van

-Coc receptor cua he adrenergic chia làm 2 loai: o & o

-> Thuoc t/dung tron he cholinergic:

+Thuoc kthoch he Muscarinic ( he M)

+ Thuoc ngung hom he M

+Thuoc kthoch he nicotinic ( he N)

+Thuoc ngung hom he N

-Thuoc t/dung tron he adrenergic:

+ Thuoc cuong he adrenergic: cuong o &o, cuong o,cuong o

+Thuoc huy he adrenergic: huy o, huy o