WOH World Championship (x2 - 2K19):

[Reign 1: 91 Days - Successful Title Defences: 0, Reign 2: 77 Days - Successful Title Defences: 1].

WWE Women's Championship (x2, 1 time as Charlotte Flair, 1 time as Charlotte Flair '17 - 2K20):

Charlotte Flair - [Reign 1: 49 Days - Successful Title Defences: 0].

Charlotte Flair '17 - [Reign 1: 77 Days - Successful Title Defences: 0].

AEW Women's World Championship (x1 for Charlotte Flair - 2K20):

[Reign 1: 84 Days - Successful Title Defences: 1].

WWE Women's Championship [Back when it was called the WWF Ladies World Wrestling Championship] (x1 for Charlotte Flair/Current Champion - 2K19):

Undisputed Women's World Championship (x1 for Charlotte Flair - 2K19):

[Reign 1: 56 Days - Successful Title Defences: 2].

WWE Raw Women's Championship and WWE Smackdown Women's Championship (x1 for each in 2K20 with Charlotte Flair, x1 for the Smackdown Women's Championship in 2K19, and x2 for the Smackdown Women's Championship in 2K22/Current Champion, x1 for the Raw Women's Championship in 2K22 - 2K20, 2K19, and 2K22):

Raw Women's Championship - [Reign 1: 63 Days - Successful Title Defences: 1, Reign 2: 70 Days - Successful Title Defences: 1].

Smackdown Women's Championship - [Reign 1: 49 Days - Successful Title Defences: 0, Reign 2: 49 Days - Successful Title Defences: 0, Reign 3: 56 Days - Successful Title Defences: 0, Reign 4: 210+ Days/Current Champion - Successful Title Defences: 3+].

WWE Women's Tag Team Championships (x1 with Raquel Gonzalez - WWE 2K22 MyGM Mode):

[Reign 1: 14 Days - Successful Title Defences: 1].

NXT UK Women's Championship (x1 - 2K22):

[Reign 1: 98 Days - Successful Title Defences: 2].

[As of 21/05/2023].