The Johto region is the next in line of the Revamped Regions, supporting the same changes that Kanto features.

Most importantly however, Lugia and Ho-Oh have begun acting strange.

Gym Leaders

Falkner
Pidgey
Starly
Ducklet
Vullaby
Emolga
Corvisquire

Bugsy
Dottler
Wimpod
Joltik
Dustox
Ledian
Scyther

Whitney
Bewear
Audino
Lopunny
Loudren
Wigglytuff
Milktank

Morty
Dhelmise
Gourgeist
Jellicent
Cofagrigus
Dusclops
Mega Banette

Chuck
Grapploct
Crabominal
Lucario
Blaziken
Hitmontop
Mega Poliwrath

Jasmine
Excadrill
Perrserker
Ferrothorn
Bastidon
Skarmory
Mega Steelix

Pryce
Aurorus
Eiscue
Cryogonal
Dewgong
Glalie
Mega Mamoswine

Clair
Dracozolt
Flapple
Kommo-O
Noivern
Tyrantrum
Mega Kindra

Elite Four

Will
Malamar
Meowstic
Musharna
Grumpig
G-Slowking
Mega Xatu

Koga
A-Muk
Toxapex
Toxicroak
Drapion
Ariados
Mega Crobat

Elaine (to replace a Bruno refight)
Centiskorch
Infernape
A-Marowak
Camerupt
Magmortar
Mega Volcarona

Karen
Bisharp
Urshifu
Krookodile
Crawdaunt
Tyranitar
Mega Umbreon

Red
Charizard
Blastoise
Venusaur
Snorlax
Lapras
Mega Pikachu

New Megas
Mega Typlosian Y - Fire/Dark

Mega Typlosian X - Fire/Ghost

Mega Feraligatr - Water/Dragon

Mega Meganium - Grass/Fairy

Mega Ledian - Flying/Fighting

Mega Espeon - Psychic

Mega Ho-Oh - Fire/Fairy

Mega Lugia - Psychic/Water