A Cancer and Aries breakup: Watch out for emotional scarring or plenty of misunderstandings. 

A Cancer and Taurus breakup: There will definitely be resentment, these two don't have much of a chance of being friends after.

A Cancer and Gemini breakup: One stops talking to the other. 

A Cancer and Cancer breakup: Very emotional, possible grudge holding, and takes a while for both to move on. 

A Cancer and Leo breakup: Heart-breaking and both will hold a grudge. 

A Cancer and Virgo breakup: Rigid and possibly a lot of unclear messages.

A Cancer and Libra breakup: Both knew it was coming but they avoid the issue for a long time until things just break. 

A Cancer and Scorpio breakup: Life-changing and one of the breaking points was probably manipulation or broken trust. 

A Cancer and Sagittarius breakup: Could get awkward but most likely ends quietly. 

A Cancer and Capricorn breakup: It is likely a drawn out breakup. 

A Cancer and Aquarius breakup: Emotions are discussed, possibly some coldness, but they can end things on "good terms" sort of speak. 

A Cancer and Pisces breakup: Rocky, a lot of emotional turmoil, and probably a good amount of manipulation.