#1: "The Queen/The Opportunity" Charlotte Flair [Reign #1]: She was the first champion in 2K22, so this is being counted as a new reign, just because...

[Days/Weeks Reign: 8 Weeks/56 Days - Successful Title Defences: 0].

#2: Peyton Royce [Reign #1]: Shockingly, but not unpleasantly, won from Charlotte Flair at SmackDown - Thunderdome in a No Holds Barred Match, with Peyton picking up the surprising win after hitting the "Swinging Leg" on Charlotte before winning by pinfall in about 5 minutes!

[Days/Weeks Held: 11+ Weeks/77+ Days - Successful Title Defences: 2+].

[As of 22/11/2022].